Abstract: The development and utilization of clean energy is one of the important ways of energy structure adjustment, and geothermal energy stands as a priority field for urban new energy sources. Usually in the early stage of geothermal exploration, it is difficult to identify the occurrence characteristics of geothermal reservoirs due to the small number of available boreholes. This paper carries out the two-dimensional seismic exploration in urban built-up areas, and experimentally combines the acoustic impedance inversion technology to predict the thickness and distribution range of geothermal reservoirs in the study area. The results show that seismic exploration combined with acoustic impedance inversion technology is an effective exploration method for geothermal reservoir prediction.